An NCI study in mice that found a connection between gut bacteria and antitumor immune responses in the liver has implications for understanding mechanisms that lead to liver cancer and for potential treatments. The study was published in Science.
The 2018 Annual Report to the Nation on the Status of Cancer finds overall cancer death rates continue to decline and cancer incidence dropped in men and remained stable in women. A companion study reports on recent changes in prostate cancer trends.
In a study in The New England Journal of Medicine, NCI researchers identified genetic subtypes of diffuse large B-cell lymphoma (DLBCL), the most common type of lymphoma, that could help explain why some patients with the disease respond to treatment and others don’t.
The Cancer Genome Atlas (TCGA), supported by NIH’s NHGRI and NCI, concludes with an in-depth genomic analysis of 33 cancer types called the PanCancer Atlas. Findings are being published as a collection of 27 papers across multiple Cell journals.
Interim results from a clinical trial for patients with desmoid tumors or aggressive fibromatosis (DT/DF) show that the drug sorafenib tosylate (Nexavar) extended progression-free survival compared with a placebo.
Dr. Douglas R. Lowy and Dr. John T. Schiller of the National Cancer Institute will receive the 2018 Szent-Gyorgyi Prize for Progress in Cancer Research for the development of HPV vaccines.